Antenatal prediction of postpartum depression with blood DNA methylation biomarkers
نویسندگان
چکیده
منابع مشابه
Oxytocin receptor DNA methylation in postpartum depression.
The oxytocin receptor (OXTR) is a key regulator of stress and anxiety and may be regulated by both psychosocial risk factors and gonadal hormones, making it an attractive candidate for study in postpartum depression (PPD). The objective of this study was to investigate both serum hormone and PPD specific DNA methylation variation in the OXTR. Illumina HM450 microarray data generated in a prospe...
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Introduction: Postpartum depression is the most common serious mental disorder in the postpartum period. Postpartum depression is associated with serious complications for mother, baby and her family. This study is designed to investigate the effect of antenatal education on pregnancy depression in theses who referred to Dezful health canters. Methods: This case-control study was carried ...
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Introduction: Evidence shows that some men suffer from Postpartum Depression (PPD), and that the adverse effects of this unknown phenomenon affect them and their family. Objective: The purpose of this study was to determine paternal PPD and its relationship with some factors, especially maternal PPD. Materials and Methods: This cross-sectional study was performed on 205 couples who were selec...
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BACKGROUND Sensitive, specific blood-based tests are difficult to develop unless steps are taken to maximize performance characteristics at every stage of marker discovery and development. We describe a sieving strategy for identifying high-performing marker assays that detect colorectal cancer (CRC)-specific methylated DNA in plasma. METHODS We first used restriction enzyme-based discovery m...
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Adverse environmental exposures in pregnancy can significantly alter the development of the fetus resulting in impaired child neurodevelopment. Such exposures can lead to epigenetic alterations like DNA methylation, which may be a marker of poor cognitive, motor and behavioral outcomes in the infant. Here we review studies that have assessed DNA methylation in cord blood following maternal expo...
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ژورنال
عنوان ژورنال: Molecular Psychiatry
سال: 2013
ISSN: 1359-4184,1476-5578
DOI: 10.1038/mp.2013.62